Jason Hope’s medical philanthropy is making a real difference in the fight against disease

Heart-disease-related illnesses are among the most deadly killers of any ailment in the United States. Heart attack, stroke and other diseases directly caused by arterial malfunction secondary to atherosclerotic disease collectively kill more people in the United States each year than any other illness. In fact, heart disease, by itself, is the number one killer of Americans, leading to the deaths of hundreds of thousands of people each year.

Jason Hope, one of Arizona’s most prolific successful entrepreneurs, has decided to put his money where his mouth is, donating more than $500,000 to the SENS Foundation, one of the nation’s most respected research institutions, for research into the molecular processes that underpin atherosclerosis. The medical establishment has long understood that the processes that make up the formation of atherosclerotic plaque, including the slight damage to endothelial tissue and the inflammatory response that follows, are also the primary suspected culprits in a plethora of diseases, particularly those seen in the geriatric cohort.

Hope has long been an avid consumer of the medical literature, such as the Lancet and the New England Journal of Medicine. Through his own studies, Hope has determined that one of the best and most cost effective ways to increase the overall survival of the U.S. population is through medical efforts to stem the scourge of heart disease, stroke and other illnesses directly caused by atherosclerosis. But Hope also understands that if the underlying molecular processes can be understood with sufficient granularity, it may be possible to largely eliminate many of the illnesses that afflict the elderly, perhaps leading to dramatic increases in life expectancy for everyone in the United States.

Hope has stated that diseases ranging from glaucoma to rheumatoid arthritis and even wrinkly skin are a direct result of low-level inflammation. This is an inevitable side effect of the aging process, where small injuries to various tissue types elicit an inflammatory response in the body, causing the formation of scar tissue of one kind or another. After a lifetime of these small insults to the tissues’ health and subsequent inflammatory response, the tissue eventually becomes sclerotic and unable to perform its vital tasks.

About Jason Hope: https://twitter.com/jasonhope